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human FCAR shRNA silencing Adenovirus

Name 
Ad-h-FCAR-shRNA
Cat No 
shADV-208844
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human FCAR.

shADV-208844
Ad-h-FCAR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FCAR (Fc fragment of IgA receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD89; CTB-61M7.2; FcalphaRI
Description (Vector)
FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
2204
Gene Name (Vector)
Fc fragment of IgA receptor
Gene Symbol
FCAR
HGNC ID
HGNC:3608
ORF Size (aa)
864
ORF Size (bp)
864 bp
RefSeq ID
NM_002000
RefSeq Synonyms
NM_133279, NM_133278, NM_133277, NM_133274, NM_133273, NM_133272, NM_133271, NM_133269, NM_002000, BC027953,
Species
human
UniGene ID
Hs.659872

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.