human FBXW10 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FBXW10.
shADV-208829
Ad-h-FBXW10-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FBXW10 (F-box and WD repeat domain containing 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Fbw10; HREP; SM25H2; SM2SH2;
Description (Vector)
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied by OMIM, Mar 2008)
Gene ID
10517
Gene Name (Vector)
F-box and WD repeat domain containing 10
Gene Symbol
FBXW10
HGNC ID
HGNC:1211
ORF Size (aa)
3186
ORF Size (bp)
3186 bp
RefSeq ID
NM_031456
RefSeq Synonyms
NM_031456, NM_001267586, NM_001267585, BC028364,
Species
human
UniGene ID
Hs.592128
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.