human FBXO18 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FBXO18.
shADV-208783
Ad-h-FBXO18-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FBXO18 (F-box protein, helicase, 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FBH1; Fbx18; hFBH1
Description (Vector)
FBXO18 encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
84893
Gene Name (Vector)
F-box protein, helicase, 18
Gene Symbol
FBXO18
HGNC ID
HGNC:13620
ORF Size (aa)
2910
ORF Size (bp)
2910 bp
RefSeq ID
NM_032807
RefSeq Synonyms
NM_178150, NM_032807, NM_001258453, NM_001258452, BC113377, BC113375, BC110884,
Species
human
UniGene ID
Hs.498543
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.