human FBXL6 shRNA silencing Adenovirus

Name 
Ad-h-FBXL6-shRNA
Cat No 
shADV-208765
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human FBXL6.

shADV-208765
Ad-h-FBXL6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FBXL6 (F-box and leucine rich repeat protein 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FBL6; FBL6A; PP14630
Description (Vector)
FBXL6 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants.
Gene ID
26233
Gene Name (Vector)
F-box and leucine rich repeat protein 6
Gene Symbol
FBXL6
HGNC ID
HGNC:13603
ORF Size (aa)
1620
ORF Size (bp)
1620 bp
RefSeq ID
NM_012162
RefSeq Synonyms
NM_024555, NM_012162, BC033066,
Species
human
UniGene ID
Hs.12271

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.