human FBXL12 shRNA silencing Adenovirus

Name 
Ad-h-FBXL12-shRNA
Cat No 
shADV-208746
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human FBXL12.

shADV-208746
Ad-h-FBXL12-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FBXL12 (F-box and leucine rich repeat protein 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Fbl12
Description (Vector)
Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied by OMIM, Mar 2008)
Gene ID
54850
Gene Name (Vector)
F-box and leucine rich repeat protein 12
Gene Symbol
FBXL12
HGNC ID
HGNC:13611
ORF Size (aa)
981
ORF Size (bp)
981 bp
RefSeq ID
NM_017703
RefSeq Synonyms
NM_017703, NM_001316942, NM_001316941, NM_001316940, NM_001316939, NM_001316938, NM_001316937, NM_001316936, BC001586,
Species
human
UniGene ID
Hs.12439

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.