human F7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human F7.
shADV-208234
Ad-h-F7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human F7 (coagulation factor VII). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SPCA
Description (Vector)
F7 encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
2155
Gene Name (Vector)
coagulation factor VII
Gene Symbol
F7
HGNC ID
HGNC:3544
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
RefSeq ID
NM_000131
RefSeq Synonyms
NM_019616, NM_001267554, NM_000131, BC130468,
Species
human
UniGene ID
Hs.36989
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.