human ELAVL3 shRNA silencing Adenovirus

Name
Ad-h-ELAVL3-shRNA

Cat No
shADV-207830

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ELAVL3.

shADV-207830

Ad-h-ELAVL3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ELAVL3 (ELAV like RNA binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

HUC; HUCL; PLE21

Description (Vector)

A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene ID

1995

Gene Name (Vector)

ELAV like RNA binding protein 3

Gene Symbol

ELAVL3

HGNC ID

HGNC:3314

ORF Size (aa)

705

ORF Size (bp)

705 bp

RefSeq ID

NM_001420

RefSeq Synonyms

NM_032281, NM_001420, BC011875,

Species

human

UniGene ID

Hs.1701

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.