human EIF4B shRNA silencing Adenovirus

Name 
Ad-h-EIF4B-shRNA
Cat No 
shADV-207774
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human EIF4B.

shADV-207774
Ad-h-EIF4B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EIF4B (eukaryotic translation initiation factor 4B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EIF-4B; eukaryotic translation initiation factor 4B; PRO1843
Description (eCommerce)
Eukaryotic initiation factor 4B (eIF4B) is a factor required for the binding of mRNA to ribosomes for the initiation of translation. eIF4B has been demonstrated to modulate the helicase activity of eIF4A, a component of the eIF4F complex.
Gene ID
1975
Gene Name (eCommerce)
eukaryotic translation initiation factor 4B
Gene Name (Vector)
eukaryotic translation initiation factor 4B
Gene Symbol
EIF4B
HGNC ID
HGNC:3285
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1836
ORF Size (bp)
1836 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 4B
RefSeq ID
NM_001417
RefSeq Synonyms
NM_001417, NM_001330654, NM_001300821, BC098437, BC073154, BC073139,
Research Areas
Cancer,Gene Expression,IFN Signaling,IGF-1 Signaling,Insulin Signaling,Metabolism/Metabolic Process,mRNA Binding,mTOR Signaling,PI3K/Akt Signaling,RNA Binding,RNA Processing,RNA Transport,Signal Transduction,Translational Control
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation,immunology,metabolism,signal_transduction
Species
human
Target Sentence
Eukaryotic initiation factor 4B (eIF4B) is a factor required for the binding of mRNA to ribosomes for the initiation of translation. eIF4B has been demonstrated to modulate the helicase activity of eIF4A, a component of the eIF4F complex.
UniGene ID
Hs.702041
UniProt ID (eCommerce)
P23588

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.