human EIF2C3 shRNA silencing Adenovirus

Name 
Ad-h-EIF2C3-shRNA
Cat No 
shADV-207723
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human AGO3.

shADV-207723
Ad-h-EIF2C3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AGO3 (argonaute 3, RISC catalytic component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EIF2C3
Description (Vector)
EIF2C3 encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. EIF2C3 is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
192669
Gene Name (Vector)
argonaute 3, RISC catalytic component
Gene Symbol
AGO3
HGNC ID
HGNC:18421
ORF Size (aa)
1881
ORF Size (bp)
1881 bp
RefSeq ID
NM_024852
RefSeq Synonyms
NM_177422, NM_024852, BC172480, BC156434, BC066888,
Species
human
UniGene ID
Hs.657659

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.