human EFHD2 shRNA silencing Adenovirus

Name 
Ad-h-EFHD2-shRNA
Cat No 
shADV-207626
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human EFHD2.

shADV-207626
Ad-h-EFHD2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EFHD2 (EF-hand domain family member D2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EF hand domain containing 2; EF-hand domain-containing protein D2; swiprosin 1; Swiprosin-1; SWS1; testicular tissue protein Li 62
Description (eCommerce)
Swiprosin-1 may regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Swiprosin plays a role as negative regulator of the canonical NF-kappa-B-activating branch. It also controls spontaneous apoptosis through the regulation of BCL2L1 abundance [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96C19].
Gene ID
79180
Gene Name (eCommerce)
EF-hand domain family member D2
Gene Name (Vector)
EF-hand domain family member D2
Gene Symbol
EFHD2
HGNC ID
HGNC:28670
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
723
ORF Size (bp)
723 bp
Protein Name (eCommerce)
EF-hand domain-containing protein D2
RefSeq ID
NM_024329
RefSeq Synonyms
NM_024329, BC068473, BC023611, BC014923, BC007233,
Research Areas
Alzheimer's Disease,Neurobiology
Research Areas (Faceted)
neurobiology
Species
human
Target Sentence
Swiprosin-1 may regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Swiprosin plays a role as negative regulator of the canonical NF-kappa-B-activating branch. It also controls spontaneous apoptosis through the regulation of BCL2L1 abundance [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96C19].
UniGene ID
Hs.465374
UniProt ID (eCommerce)
Q96C19

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.