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human EDF1 shRNA silencing Adenovirus

Name 
Ad-h-EDF1-shRNA
Cat No 
shADV-207562
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human EDF1.

shADV-207562
Ad-h-EDF1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EDF1 (endothelial differentiation related factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CFAP280; EDF-1; endothelial differentiation-related factor 1; MBF1; multiprotein bridging factor 1; Multiprotein-bridging factor 1
Description (eCommerce)
Endothelial differentiation-related factor 1 (EDF-1) is a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. EDF-1 has also been found to act as a transcriptional co-activator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators [taken from NCBI Entrez Gene (Gene ID: 8721)].
Description (Vector)
EDF1 encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.
Gene ID
8721
Gene Name (eCommerce)
endothelial differentiation related factor 1
Gene Name (Vector)
endothelial differentiation related factor 1
Gene Symbol
EDF1
HGNC ID
HGNC:3164
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
447
Protein Name (eCommerce)
Endothelial differentiation-related factor 1
RefSeq ID
NM_003792
RefSeq Synonyms
NM_153200, NM_003792, NM_001281299, NM_001281298, NM_001281297, BC015500,
Research Areas
Metabolism/Metabolic Process,Methyltransferase,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Endothelial differentiation-related factor 1 (EDF-1) is a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. EDF-1 has also been found to act as a transcriptional co-activator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators [taken from NCBI Entrez Gene (Gene ID: 8721)].
UniGene ID
Hs.174050
UniProt ID (eCommerce)
O60869

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.