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human EBAG9 shRNA silencing Adenovirus

Name 
Ad-h-EBAG9-shRNA
Cat No 
shADV-207508
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human EBAG9.

shADV-207508
Ad-h-EBAG9-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EBAG9 (estrogen receptor binding site associated, antigen, 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cancer-associated surface antigen RCAS1; EB9; estrogen receptor-binding fragment-associated gene 9 protein; PDAF; receptor-binding cancer antigen expressed on SiSo cells
Description (eCommerce)
The gene for RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) was identified as an estrogen-responsive gene. Regulation by estrogen of transcription of RCAS1 is mediated by the estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of the RCAS1 gene, EBAG9 (estrogen receptor binding site associated antigen 9). RCAS1 is a tumor-associated antigen that is expressed at high frequency in a variety of cancers [taken from NCBI Entrez Gene (GeneID: 9166)].
Description (Vector)
EBAG9 was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
Gene ID
9166
Gene Name (eCommerce)
estrogen receptor binding site associated, antigen, 9
Gene Name (Vector)
estrogen receptor binding site associated, antigen, 9
Gene Symbol
EBAG9
HGNC ID
HGNC:3123
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
642
ORF Size (bp)
642 bp
Protein Name (eCommerce)
Receptor-binding cancer antigen expressed on SiSo cells
RefSeq ID
NM_004215
RefSeq Synonyms
NM_198120, NM_004215, NM_001278938, BC022506, BC017729, BC005249,
Research Areas
Apoptosis,Golgi Apparatus
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
The gene for RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) was identified as an estrogen-responsive gene. Regulation by estrogen of transcription of RCAS1 is mediated by the estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of the RCAS1 gene, EBAG9 (estrogen receptor binding site associated antigen 9). RCAS1 is a tumor-associated antigen that is expressed at high frequency in a variety of cancers [taken from NCBI Entrez Gene (GeneID: 9166)].
UniGene ID
Hs.409368
UniProt ID (eCommerce)
O00559

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.