human E2F7 shRNA silencing Adenovirus

Name 
Ad-h-E2F7-shRNA
Cat No 
shADV-207500
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human E2F7.

shADV-207500
Ad-h-E2F7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human E2F7 (E2F transcription factor 7). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
E2F-7; transcription factor E2F7
Description (eCommerce)
E2F7, along with E2F8, functions as an inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. E2F7 directly represses E2F1 transcription and appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96AV8].
Description (Vector)
E2F transcription factors, such as E2F7, play an essential role in the regulation of cell cycle progression (Di Stefano et al., 2003 (PubMed 14633988)).(supplied by OMIM, May 2008)
Gene ID
144455
Gene Name (eCommerce)
E2F transcription factor 7
Gene Name (Vector)
E2F transcription factor 7
Gene Symbol
E2F7
HGNC ID
HGNC:23820
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2736
ORF Size (bp)
2736 bp
Protein Name (eCommerce)
Transcription factor E2F7
RefSeq ID
NM_203394
RefSeq Synonyms
NM_203394, BC136367, BC136366,
Research Areas
Angiogenesis,Cancer,Cell Cycle,DNA Damage/Repair,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
E2F7, along with E2F8, functions as an inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. E2F7 directly represses E2F1 transcription and appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96AV8].
UniGene ID
Hs.416375
UniProt ID (eCommerce)
Q96AV8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.