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human DSC1 shRNA silencing Adenovirus

Name 
Ad-h-DSC1-shRNA
Cat No 
shADV-207335
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human DSC1.

shADV-207335
Ad-h-DSC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DSC1 (desmocollin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CDHF1; DG2/DG3
Description (Vector)
DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
Gene ID
1823
Gene Name (Vector)
desmocollin 1
Gene Symbol
DSC1
HGNC ID
HGNC:3035
ORF Size (aa)
2682
ORF Size (bp)
2682 bp
RefSeq ID
NM_004948
RefSeq Synonyms
NM_024421, NM_004948, BC148349,
Species
human
UniGene ID
Hs.567260

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.