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human DOC2A shRNA silencing Adenovirus

Name 
Ad-h-DOC2A-shRNA
Cat No 
shADV-207218
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DOC2A.

shADV-207218
Ad-h-DOC2A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DOC2A (double C2 domain alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Doc2
Description (Vector)
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.
Gene ID
8448
Gene Name (Vector)
double C2 domain alpha
Gene Symbol
DOC2A
HGNC ID
HGNC:2985
ORF Size (aa)
1203
RefSeq ID
NM_003586
RefSeq Synonyms
NM_003586, NM_001282068, NM_001282063, NM_001282062, BC063436, BC055284, BC041769,
Species
human
UniGene ID
Hs.355281

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.