human DNTT shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DNTT.
shADV-207215
Ad-h-DNTT-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DNTT (DNA nucleotidylexotransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TDT
Description (Vector)
DNTT is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Gene ID
1791
Gene Name (Vector)
DNA nucleotidylexotransferase
Gene Symbol
DNTT
HGNC ID
HGNC:2983
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
RefSeq ID
NM_004088
RefSeq Synonyms
NM_004088, NM_001017520, BC012920,
Species
human
UniGene ID
Hs.534206
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.