human DNMBP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DNMBP.
shADV-207206
Ad-h-DNMBP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DNMBP (dynamin binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARHGEF36; dynamin-binding protein; scaffold protein TUBA; TUBA
Description (eCommerce)
The protein, Tuba, was identified in a search for proteins containing a domain related to the BAR (Bin/amphyphysin/Rvs) domain of amphiphysin-1. Tuba was named according to a tradition of naming large synaptic proteins after musical instruments. Tuba is concentrated at synapses in the brain has been found to function as a scaffolding protein that brings dynamin together with actin regulatory proteins.
Description (Vector)
DNMBP belongs to the DBL (MIM 311030) family of guanine nucleotide exchange factors and plays a role in the regulation of cell junctions (Otani et al., 2006 (PubMed 17015620)).(supplied by OMIM, Mar 2008)
Gene ID
23268
Gene Name (eCommerce)
dynamin binding protein
Gene Name (Vector)
dynamin binding protein
Gene Symbol
DNMBP
HGNC ID
HGNC:30373
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2472
ORF Size (bp)
2472 bp
Protein Name (eCommerce)
Dynamin-binding protein
RefSeq ID
NM_015221
RefSeq Synonyms
NM_015221, NM_001318327, NM_001318326, BC041628,
Research Areas
Cytoskeleton,Golgi Apparatus,Neurobiology,Rho Signaling,Signal Transduction,Synapse
Research Areas (Faceted)
cell_biology,neurobiology,signal_transduction
Species
human
Target Sentence
The protein, Tuba, was identified in a search for proteins containing a domain related to the BAR (Bin/amphyphysin/Rvs) domain of amphiphysin-1. Tuba was named according to a tradition of naming large synaptic proteins after musical instruments. Tuba is concentrated at synapses in the brain has been found to function as a scaffolding protein that brings dynamin together with actin regulatory proteins.
UniGene ID
Hs.500771
UniProt ID (eCommerce)
Q6XZF7
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.