human DNM1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DNM1.
shADV-207200
Ad-h-DNM1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DNM1 (dynamin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DNM; EIEE31
Description (Vector)
DNM1 encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
1759
Gene Name (Vector)
dynamin 1
Gene Symbol
DNM1
HGNC ID
HGNC:2972
ORF Size (aa)
2556
ORF Size (bp)
2556 bp
RefSeq ID
NM_004408
RefSeq Synonyms
NM_004408, NM_001288739, NM_001288738, NM_001288737, NM_001005336, BC063850, BC050279,
Species
human
UniGene ID
Hs.522413
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.