human DKK2 shRNA silencing Adenovirus

Name 
Ad-h-DKK2-shRNA
Cat No 
shADV-207024
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human DKK2.

shADV-207024
Ad-h-DKK2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DKK2 (dickkopf WNT signaling pathway inhibitor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DKK-2
Description (Vector)
DKK2 encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Gene ID
27123
Gene Name (Vector)
dickkopf WNT signaling pathway inhibitor 2
Gene Symbol
DKK2
HGNC ID
HGNC:2892
ORF Size (aa)
780
ORF Size (bp)
780 bp
RefSeq ID
NM_014421
RefSeq Synonyms
NM_014421, BC126330, BC126328, BC075078, BC075077,
Species
human
UniGene ID
Hs.211869

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.