human DEFB1 shRNA silencing Adenovirus

Name 
Ad-h-DEFB1-shRNA
Cat No 
shADV-206806
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DEFB1.

shADV-206806
Ad-h-DEFB1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DEFB1 (defensin beta 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BD1; DEFB-1; DEFB101; HBD1
Description (Vector)
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
Gene ID
1672
Gene Name (Vector)
defensin beta 1
Gene Symbol
DEFB1
HGNC ID
HGNC:2766
ORF Size (aa)
207
RefSeq ID
NM_005218
RefSeq Synonyms
NM_005218, BC047677, BC033298,
Species
human
UniGene ID
Hs.32949

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.