human DCXR shRNA silencing Adenovirus

Name 
Ad-h-DCXR-shRNA
Cat No 
shADV-206689
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DCXR.

shADV-206689
Ad-h-DCXR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DCXR (dicarbonyl and L-xylulose reductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DCR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR
Description (Vector)
DCXR acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
51181
Gene Name (Vector)
dicarbonyl and L-xylulose reductase
Gene Symbol
DCXR
HGNC ID
HGNC:18985
ORF Size (aa)
735
ORF Size (bp)
735 bp
RefSeq ID
NM_016286
RefSeq Synonyms
NM_016286, NM_001195218, BC001470,
Species
human
UniGene ID
Hs.9857

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.