human CYP1B1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CYP1B1.
shADV-206457
Ad-h-CYP1B1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CYP1B1 (cytochrome P450 family 1 subfamily B member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CP1B; CYPIB1; GLC3A; P4501B1
Description (Vector)
CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
Gene ID
1545
Gene Name (Vector)
cytochrome P450 family 1 subfamily B member 1
Gene Symbol
CYP1B1
HGNC ID
HGNC:2597
ORF Size (aa)
1632
ORF Size (bp)
1632 bp
RefSeq ID
NM_000104
RefSeq Synonyms
NM_000104, BC012049,
Species
human
UniGene ID
Hs.715731
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.