human CST6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CST6.
shADV-206180
Ad-h-CST6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CST6 (cystatin E/M). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
Gene ID
1474
Gene Name (Vector)
cystatin E/M
Gene Symbol
CST6
HGNC ID
HGNC:2478
ORF Size (aa)
450
RefSeq ID
NM_001323
RefSeq Synonyms
NM_001323, BC031334,
Species
human
UniGene ID
Hs.139389
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.