human KLF8 Over-expression AAV

Name 
AAV-h-KLF8
Cat No 
AAV-213196
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KLF8.

AAV-213196
AAV-h-KLF8

Ready-to-use AAV expressing Human KLF8 (Kruppel like factor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BKLF3; ZNF741
Description (Vector)
KLF8 encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.
Gene ID
11279
Gene Name (Vector)
Kruppel like factor 8
Gene Symbol
KLF8
HGNC ID
HGNC:6351
ORF Size (aa)
1080
ORF Size (bp)
1080 bp
RefSeq ID
NM_007250
RefSeq Synonyms
NM_007250, NM_001324105, NM_001324104, NM_001324102, NM_001324100, NM_001324099, NM_001159296, BC112109, BC105130, BC031355,
Species
human
UniGene ID
Hs.646614

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.