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human CP shRNA silencing Adenovirus

Name 
Ad-h-CP-shRNA
Cat No 
shADV-205865
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CP.

shADV-205865
Ad-h-CP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CP (ceruloplasmin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ceruloplasmin; ceruloplasmin (ferroxidase); CP-2; Ferroxidase
Description (eCommerce)
Ceruloplasmin is a serum protein that functions as the primary mechanism for copper transport, and plays a role in iron transport as well. Deficiencies can often result in arthritis or Wilson's disease.
Description (Vector)
CP is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Gene ID
1356
Gene Name (eCommerce)
ceruloplasmin
Gene Name (Vector)
ceruloplasmin
Gene Symbol
CP
HGNC ID
HGNC:2295
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3198
ORF Size (bp)
3198 bp
Protein Name (eCommerce)
Ceruloplasmin
RefSeq ID
NM_000096
RefSeq Synonyms
NM_000096, BC146663, BC142714,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Ceruloplasmin is a serum protein that functions as the primary mechanism for copper transport, and plays a role in iron transport as well. Deficiencies can often result in arthritis or Wilson's disease.
UniGene ID
Hs.558314
UniProt ID (eCommerce)
P00450

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.