human COX5B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human COX5B.
shADV-205835
Ad-h-COX5B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human COX5B (cytochrome c oxidase subunit 5B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
COXVB; Cytochrome c oxidase polypeptide Vb; cytochrome c oxidase polypeptide VB, mitochondrial; cytochrome c oxidase subunit 5B, mitochondrial; cytochrome c oxidase subunit Vb; epididymis secretory sperm binding protein
Description (eCommerce)
Cytochrome c oxidase subunit 5B (COX5B) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P10606].
Description (Vector)
Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme.
Gene ID
1329
Gene Name (eCommerce)
cytochrome c oxidase subunit 5B
Gene Name (Vector)
cytochrome c oxidase subunit 5B
Gene Symbol
COX5B
HGNC ID
HGNC:2269
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
390
Protein Name (eCommerce)
Cytochrome c oxidase subunit 5B, mitochondrial
RefSeq ID
NM_001862
RefSeq Synonyms
NM_001862, BC006229,
Research Areas
Alzheimer's Disease,Cardiology,Cardiovascular,Huntington's Disease,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Neurodegeneration,Parkinson's Disease
Research Areas (Faceted)
neurobiology,cardiovascular,metabolism,cell_biology
Species
human
Target Sentence
Cytochrome c oxidase subunit 5B (COX5B) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P10606].
UniGene ID
Hs.1342
UniProt ID (eCommerce)
P10606
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.