human COX4I2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human COX4I2.
shADV-205829
Ad-h-COX4I2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human COX4I2 (cytochrome c oxidase subunit 4I2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
COX4; COX4-2; COX4B; COX4L2; COXIV-2; dJ857M17.2
Description (Vector)
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.
Gene ID
84701
Gene Name (Vector)
cytochrome c oxidase subunit 4I2
Gene Symbol
COX4I2
HGNC ID
HGNC:16232
ORF Size (aa)
516
ORF Size (bp)
516 bp
RefSeq ID
NM_032609
RefSeq Synonyms
NM_032609, BC057779,
Species
human
UniGene ID
Hs.277101
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.