human COMP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human COMP.
shADV-205749
Ad-h-COMP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human COMP (cartilage oligomeric matrix protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EDM1; EPD1; MED; MGC131819; MGC149768; PSACH; THBS5;
Description (Vector)
COMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Gene ID
1311
Gene Name (Vector)
cartilage oligomeric matrix protein
Gene Symbol
COMP
ORF Size (aa)
2274
ORF Size (bp)
2274 bp
RefSeq ID
NM_000095
RefSeq Synonyms
NM_000095, BC125092, BC110847,
Species
human
UniGene ID
Hs.1584
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.