human COL9A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human COL9A1.
shADV-205720
Ad-h-COL9A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human COL9A1 (collagen type IX alpha 1 chain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DJ149L1.1.2; EDM6; MED; STL4
Description (Vector)
COL9A1 encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Gene ID
1297
Gene Name (Vector)
collagen type IX alpha 1 chain
Gene Symbol
COL9A1
HGNC ID
HGNC:2217
ORF Size (aa)
2037
ORF Size (bp)
2037 bp
RefSeq ID
NM_001851
RefSeq Synonyms
NM_078485, NM_001851, BC063646, BC015409,
Species
human
UniGene ID
Hs.590892
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.