human KLF11 Over-expression AAV

Name 
AAV-h-KLF11
Cat No 
AAV-213175
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KLF11.

AAV-213175
AAV-h-KLF11

Ready-to-use AAV expressing Human KLF11 (Kruppel like factor 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FKLF; FKLF1; MODY7; TIEG2; Tieg3
Description (Vector)
KLF11 is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
8462
Gene Name (Vector)
Kruppel like factor 11
Gene Symbol
KLF11
HGNC ID
HGNC:11811
ORF Size (aa)
1539
ORF Size (bp)
1539 bp
RefSeq ID
NM_003597
RefSeq Synonyms
NM_003597, NM_001177718, NM_001177716, BC074922, BC069383, BC063286,
Species
human
UniGene ID
Hs.12229

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.