human COL6A2 shRNA silencing Adenovirus

Name 
Ad-h-COL6A2-shRNA
Cat No 
shADV-205713
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human COL6A2.

shADV-205713
Ad-h-COL6A2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human COL6A2 (collagen type VI alpha 2 chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BTHLM1; PP3610; UCMD1
Description (Vector)
COL6A2 encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.
Gene ID
1292
Gene Name (Vector)
collagen type VI alpha 2 chain
Gene Symbol
COL6A2
HGNC ID
HGNC:2212
ORF Size (aa)
3060
ORF Size (bp)
3060 bp
RefSeq ID
NM_001849
RefSeq Synonyms
NM_058175, NM_058174, NM_001849, BC065509,
Species
human
UniGene ID
Hs.420269

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.