human CNOT4 shRNA silencing Adenovirus

Name 
Ad-h-CNOT4-shRNA
Cat No 
shADV-205609
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CNOT4.

shADV-205609
Ad-h-CNOT4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CNOT4 (CCR4-NOT transcription complex subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CLONE243; NOT4; NOT4H
Description (Vector)
CNOT4 is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
4850
Gene Name (Vector)
CCR4-NOT transcription complex subunit 4
Gene Symbol
CNOT4
HGNC ID
HGNC:7880
ORF Size (aa)
1719
ORF Size (bp)
1719 bp
RefSeq ID
NM_013316
RefSeq Synonyms
NM_013316, NM_001190850, NM_001190849, NM_001190848, NM_001190847, NM_001008225, BC035590,
Species
human
UniGene ID
Hs.490224

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.