human CLDN3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CLDN3.
shADV-205382
Ad-h-CLDN3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CLDN3 (claudin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C7orf1; CPE-R2; CPETR2; HRVP1; RVP1
Description (Vector)
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Gene ID
1365
Gene Name (Vector)
claudin 3
Gene Symbol
CLDN3
HGNC ID
HGNC:2045
ORF Size (aa)
663
RefSeq ID
NM_001306
RefSeq Synonyms
NM_001306, BC016056,
Species
human
UniGene ID
Hs.647023
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.