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human CHRNA6 shRNA silencing Adenovirus

Name 
Ad-h-CHRNA6-shRNA
Cat No 
shADV-205215
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CHRNA6.

shADV-205215
Ad-h-CHRNA6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CHNRA6
Description (Vector)
CHRNA6 encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.
Gene ID
8973
Gene Name (Vector)
cholinergic receptor nicotinic alpha 6 subunit
Gene Symbol
CHRNA6
HGNC ID
HGNC:15963
ORF Size (aa)
1485
ORF Size (bp)
1485 bp
RefSeq ID
NM_004198
RefSeq Synonyms
NM_004198, NM_001199279, BC014456,
Species
human
UniGene ID
Hs.103128

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.