human CFHR3 shRNA silencing Adenovirus

Name 
Ad-h-CFHR3-shRNA
Cat No 
shADV-205048
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CFHR3.

shADV-205048
Ad-h-CFHR3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CFHR3 (complement factor H related 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CFHL3; DOWN16; FHR-3; FHR3; HLF4
Description (Vector)
CFHR3 is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
10878
Gene Name (Vector)
complement factor H related 3
Gene Symbol
CFHR3
HGNC ID
HGNC:16980
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_021023
RefSeq Synonyms
NM_021023, NM_001166624, BC070259, BC058009, BC020687,
Species
human
UniGene ID
Hs.709217

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.