human CES3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CES3.
shADV-205022
Ad-h-CES3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CES3 (carboxylesterase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ES31
Description (Vector)
CES3 encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. CES3 is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.
Gene ID
23491
Gene Name (Vector)
carboxylesterase 3
Gene Symbol
CES3
HGNC ID
HGNC:1865
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_024922
RefSeq Synonyms
NM_024922, NM_001185177, NM_001185176, BC053670,
Species
human
UniGene ID
Hs.268700
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.