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human CEP350 shRNA silencing Adenovirus

Name 
Ad-h-CEP350-shRNA
Cat No 
shADV-204993
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CEP350.

shADV-204993
Ad-h-CEP350-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CEP350 (centrosomal protein 350). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAP350; centrosomal protein 350kDa; centrosome-associated protein 350; Centrosome-associated protein of 350 kDa; Cep350; GM133
Description (eCommerce)
CAP350 (Centrosome-Associated Protein 350) has been shown to localize to the centrosome as well as to dots in the pericentrosomal area. CAP350 functions to stabilize and anchor microtubules to the centrosome and participates in the maintenance of a pericentrosomal Golgi ribbon.
Description (Vector)
The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined.
Gene ID
9857
Gene Name (eCommerce)
centrosomal protein 350
Gene Name (Vector)
centrosomal protein 350
Gene Symbol
CEP350
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
9351
ORF Size (bp)
9351 bp
Protein Name (eCommerce)
Centrosome-associated protein 350
RefSeq ID
NM_014810
RefSeq Synonyms
NM_014810, BC172424,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
CAP350 (Centrosome-Associated Protein 350) has been shown to localize to the centrosome as well as to dots in the pericentrosomal area. CAP350 functions to stabilize and anchor microtubules to the centrosome and participates in the maintenance of a pericentrosomal Golgi ribbon.
UniGene ID
Hs.413045
UniProt ID (eCommerce)
Q5VT06

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.