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human CENPE shRNA silencing Adenovirus

Name 
Ad-h-CENPE-shRNA
Cat No 
shADV-204954
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CENPE.

shADV-204954
Ad-h-CENPE-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CENPE (centromere protein E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CENP-E; Centromere autoantigen E (312kD); Centromere protein E; centromere protein E, 312kDa; centromere-associated protein E; KIF10; kinesin family member 10; kinesin-7; kinesin-related protein CENPE; MCPH13; PPP1R61; protein phosphatase 1, regulatory subunit 61
Description (eCommerce)
Centromere-associated protein E (CENP-E) is a mitotic kinesin protein and component of the kinetochore. As a microtubule-based motor, CENP-E is important to chromosome congression and functions as a tether that holds kinetochores onto growing and shrinking microtubules.
Description (Vector)
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.
Gene ID
1062
Gene Name (eCommerce)
centromere protein E
Gene Name (Vector)
centromere protein E
Gene Symbol
CENPE
HGNC ID
HGNC:1856
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
8103
ORF Size (bp)
8103 bp
Protein Name (eCommerce)
Centromere-associated protein E
RefSeq ID
NM_001813
RefSeq Synonyms
NM_001813, NM_001286734, BC156501,
Research Areas
Antigen Processing and Presentation,Cell Cycle,Cell Division,Cytoskeleton,Immunology,Kinase/Phosphatase,PLK1 Signaling,Signal Transduction,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,immunology,signal_transduction
Species
human
Target Sentence
Centromere-associated protein E (CENP-E) is a mitotic kinesin protein and component of the kinetochore. As a microtubule-based motor, CENP-E is important to chromosome congression and functions as a tether that holds kinetochores onto growing and shrinking microtubules.
UniGene ID
Hs.75573
UniProt ID (eCommerce)
Q02224

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.