human CEBPA shRNA silencing Adenovirus

Name
Ad-h-CEBPA-shRNA

Cat No
shADV-204935

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CEBPA.

shADV-204935

Ad-h-CEBPA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CEBPA (CCAAT/enhancer binding protein alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

C/EBP-alpha; CEBP

Description (Vector)

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

Gene ID

1050

Gene Name (Vector)

CCAAT/enhancer binding protein alpha

Gene Symbol

CEBPA

HGNC ID

HGNC:1833

ORF Size (aa)

1077

RefSeq ID

NM_004364

RefSeq Synonyms

NM_004364, NM_001287435, NM_001287424, NM_001285829, BC160133,

Species

human

UniGene ID

Hs.699463

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.