human CDC40 shRNA silencing Adenovirus

Name 
Ad-h-CDC40-shRNA
Cat No 
shADV-204755
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CDC40.

shADV-204755
Ad-h-CDC40-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CDC40 (cell division cycle 40). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cell division cycle 40 homolog; EHB3; EH-binding protein 3; hPRP17; pre-mRNA splicing factor 17; pre-mRNA-processing factor 17; PRP17; PRP17 homolog; PRPF17
Description (eCommerce)
Cell division cycle 40 homolog (CDC40) is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression [taken from NCBI Entrez Gene (Gene ID: 51362)].
Description (Vector)
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
Gene ID
51362
Gene Name (eCommerce)
cell division cycle 40
Gene Name (Vector)
cell division cycle 40
Gene Symbol
CDC40
HGNC ID
HGNC:17350
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1740
ORF Size (bp)
1740 bp
Protein Name (eCommerce)
Pre-mRNA-processing factor 17
RefSeq ID
NM_015891
RefSeq Synonyms
NM_015891, BC126114, BC117145,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,mRNA Transport,RNA Processing,RNA Transport,Spliceosome
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Cell division cycle 40 homolog (CDC40) is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression [taken from NCBI Entrez Gene (Gene ID: 51362)].
UniGene ID
Hs.428147
UniProt ID (eCommerce)
O60508

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.