human CDC37 shRNA silencing Adenovirus

Name 
Ad-h-CDC37-shRNA
Cat No 
shADV-204752
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CDC37.

shADV-204752
Ad-h-CDC37-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CDC37 (cell division cycle 37). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CDC37 (cell division cycle 37, S. cerevisiae, homolog); CDC37 cell division cycle 37 homolog; cell division cycle 37 homolog; hsp90 chaperone protein kinase-targeting subunit; hsp90 co-chaperone Cdc37; P50CDC37
Description (eCommerce)
Cell division cycle 37 protein (CDC37) is also known as Hsp90 co-chaperone Cdc37. CDC37 is highly similar to Cdc37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form a complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases [taken from NCBI Entrez Gene (GeneID: 11140)].
Description (Vector)
CDC37 is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Gene ID
11140
Gene Name (eCommerce)
cell division cycle 37
Gene Name (Vector)
cell division cycle 37
Gene Symbol
CDC37
HGNC ID
HGNC:1735
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1137
ORF Size (bp)
1137 bp
Protein Name (eCommerce)
Hsp90 co-chaperone Cdc37
RefSeq ID
NM_007065
RefSeq Synonyms
NM_007065, BC008793, BC000083,
Research Areas
Cancer,EGFR Signaling,EGFR Signaling in Cancer,IFN Signaling,LKB1 Signaling,PI3K/Akt Signaling,Protein Folding,Signal Transduction,TNF Signaling
Research Areas (Faceted)
cancer,cell_biology,immunology,signal_transduction
Species
human
Target Sentence
Cell division cycle 37 protein (CDC37) is also known as Hsp90 co-chaperone Cdc37. CDC37 is highly similar to Cdc37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form a complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases [taken from NCBI Entrez Gene (GeneID: 11140)].
UniGene ID
Hs.160958
UniProt ID (eCommerce)
Q16543

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.