human CDC14B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CDC14B.
shADV-204716
Ad-h-CDC14B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CDC14B (cell division cycle 14B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cdc14B1; Cdc14B2; CDC14B3; hCDC14B
Description (Vector)
CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Gene ID
8555
Gene Name (Vector)
cell division cycle 14B
Gene Symbol
CDC14B
HGNC ID
HGNC:1719
ORF Size (aa)
1497
ORF Size (bp)
1497 bp
RefSeq ID
NM_003671
RefSeq Synonyms
NM_033331, NM_003671, NM_001077181, BC156666,
Species
human
UniGene ID
Hs.40582
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.