human CD6 shRNA silencing Adenovirus

Name
Ad-h-CD6-shRNA

Cat No
shADV-204671

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CD6.

shADV-204671

Ad-h-CD6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD6 (CD6 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

TP120

Description (Vector)

CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

923

Gene Name (Vector)

CD6 molecule

Gene Symbol

CD6

HGNC ID

HGNC:1691

ORF Size (aa)

1920

ORF Size (bp)

1920 bp

RefSeq ID

NM_006725

RefSeq Synonyms

NM_006725, NM_001254751, NM_001254750, BC078669, BC033755,

Species

human

UniGene ID

Hs.643167

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.