human CD34 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CD34.
shADV-204640
Ad-h-CD34-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CD34 (CD34 molecule). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD antigen CD34; CD34 antigen; hematopoietic progenitor cell antigen CD34
Description (eCommerce)
CD34 is an adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. CD34 acts as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P28906].
Description (Vector)
CD34 may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
947
Gene Name (eCommerce)
CD34 molecule
Gene Name (Vector)
CD34 molecule
Gene Symbol
CD34
HGNC ID
HGNC:1662
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1158
ORF Size (bp)
1158 bp
Protein Name (eCommerce)
Hematopoietic progenitor cell antigen CD34
RefSeq ID
NM_001773
RefSeq Synonyms
NM_001773, NM_001025109, BC039146,
Research Areas
Angiogenesis,Apoptosis,Cancer,Cardiovascular,Gene Expression,Immunology,Lysosome,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,immunology,metabolism,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
CD34 is an adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. CD34 acts as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P28906].
UniGene ID
Hs.374990
UniProt ID (eCommerce)
P28906
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.