Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human CCT8 shRNA silencing Adenovirus

Name 
Ad-h-CCT8-shRNA
Cat No 
shADV-204568
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CCT8.

shADV-204568
Ad-h-CCT8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CCT8 (chaperonin containing TCP1 subunit 8). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
86
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C21orf112; Cctq; CCT-theta; chaperonin containing T-complex polypeptide 1 subunit 8; chaperonin containing TCP1, subunit 8 (theta); D21S246; PRED71; renal carcinoma antigen NY-REN-15; T-complex protein 1 subunit theta; TCP-1-theta
Description (eCommerce)
CCT8 is also known as T-complex protein 1 subunit theta (TCP1-theta) and is a molecular chaperone that assists in the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex, CCT8 may play a role in the assembly of BBSome, a complex involved in ciliogenesis and regulating the transport of vesicles to the cilia. TCP1-theta is known to play a role, in vitro, in the folding of actin and tubulin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P50990].
Gene ID
10694
Gene Name (eCommerce)
chaperonin containing TCP1 subunit 8
Gene Name (Vector)
chaperonin containing TCP1 subunit 8
Gene Symbol
CCT8
HGNC ID
HGNC:1623
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1494
ORF Size (bp)
1494 bp
Protein Name (eCommerce)
T-complex protein 1 subunit theta
RefSeq ID
NM_006585
RefSeq Synonyms
NM_006585, NM_001282909, NM_001282908, NM_001282907, BC095470, BC072001, BC012584,
Research Areas
Cytoskeleton,Immunology,Metabolism/Metabolic Process,Protein Folding,T-cell Receptor Signaling,Translational Control
Research Areas (Faceted)
cell_biology,immunology,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
CCT8 is also known as T-complex protein 1 subunit theta (TCP1-theta) and is a molecular chaperone that assists in the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex, CCT8 may play a role in the assembly of BBSome, a complex involved in ciliogenesis and regulating the transport of vesicles to the cilia. TCP1-theta is known to play a role, in vitro, in the folding of actin and tubulin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P50990].
UniGene ID
Hs.125113
UniProt ID (eCommerce)
P50990

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.