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human CCT7 shRNA silencing Adenovirus

Name 
Ad-h-CCT7-shRNA
Cat No 
shADV-204564
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CCT7.

shADV-204564
Ad-h-CCT7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CCT7 (chaperonin containing TCP1 subunit 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CCTETA; CCT-eta; CCTH; chaperonin containing t-complex polypeptide 1, eta subunit; HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; NIP7-1; T-complex protein 1 subunit eta; TCP1ETA; TCP-1-eta
Description (eCommerce)
Chaperonin containing TCP1 subunit 7 (eta) or CCT7 is a molecular chaperone. It assists with the folding of proteins upon ATP hydrolysis. CCT7 is known to play a role, in vitro, in the folding of actin and tubulin (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99832].
Description (Vector)
CCT7 encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.
Gene ID
10574
Gene Name (eCommerce)
chaperonin containing TCP1 subunit 7
Gene Name (Vector)
chaperonin containing TCP1 subunit 7
Gene Symbol
CCT7
HGNC ID
HGNC:1622
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1632
ORF Size (bp)
1632 bp
Protein Name (eCommerce)
T-complex protein 1 subunit eta
RefSeq ID
NM_006429
RefSeq Synonyms
NM_006429, NM_001166285, NM_001166284, NM_001009570, BC088351, BC019296,
Research Areas
Metabolism/Metabolic Process,Mitochondrion,Protein Folding,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Chaperonin containing TCP1 subunit 7 (eta) or CCT7 is a molecular chaperone. It assists with the folding of proteins upon ATP hydrolysis. CCT7 is known to play a role, in vitro, in the folding of actin and tubulin (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99832].
UniGene ID
Hs.368149
UniProt ID (eCommerce)
Q99832

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.