human CCL11 shRNA silencing Adenovirus

Name
Ad-h-CCL11-shRNA

Cat No
shADV-204415

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CCL11.

shADV-204415

Ad-h-CCL11-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CCL11 (C-C motif chemokine ligand 11). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

SCYA11

Description (Vector)

CCL11 is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Gene ID

6356

Gene Name (Vector)

C-C motif chemokine ligand 11

Gene Symbol

CCL11

HGNC ID

HGNC:10610

ORF Size (aa)

294

RefSeq ID

NM_002986

RefSeq Synonyms

NM_002986, BC017850,

Species

human

UniGene ID

Hs.54460

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.