human CCDC99 shRNA silencing Adenovirus

Name 
Ad-h-CCDC99-shRNA
Cat No 
shADV-204403
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SPDL1.

shADV-204403
Ad-h-CCDC99-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SPDL1 (spindle apparatus coiled-coil protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
arsenite-related gene 1 protein; CCDC99; coiled-coil domain-containing protein 99; hSpindly; protein Spindly; rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; Spindle apparatus coiled-coil domain-containing protein 1
Description (eCommerce)
Spindly has recently been identified as the human homolog of Drosophila spindly. Spindly has been shown to regulate mitotic dynein and is essential for the docking and recruitment of dynein to the kinetochore.
Gene ID
54908
Gene Name (eCommerce)
spindle apparatus coiled-coil protein 1
Gene Name (Vector)
spindle apparatus coiled-coil protein 1
Gene Symbol
SPDL1
HGNC ID
HGNC:26010
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1818
ORF Size (bp)
1818 bp
Protein Name (eCommerce)
Protein Spindly
RefSeq ID
NM_017785
RefSeq Synonyms
NM_017785, NM_001329643, NM_001329642, NM_001329641, NM_001329640, NM_001329639, BC012568,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Spindly has recently been identified as the human homolog of Drosophila spindly. Spindly has been shown to regulate mitotic dynein and is essential for the docking and recruitment of dynein to the kinetochore.
UniGene ID
Hs.368710
UniProt ID (eCommerce)
Q96EA4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.