human CCDC8 shRNA silencing Adenovirus

Name 
Ad-h-CCDC8-shRNA
Cat No 
shADV-204369
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CCDC8.

shADV-204369
Ad-h-CCDC8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CCDC8 (coiled-coil domain containing 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
3M3; coiled-coil domain-containing protein 8; p90; PPP1R20; protein phosphatase 1, regulatory subunit 20
Description (eCommerce)
CCDC8 (coiled-coil domain containing 8) contains one coiled coil domain. The function of CCDC8 has not been reported.
Description (Vector)
CCDC8 encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3).
Gene ID
83987
Gene Name (eCommerce)
coiled-coil domain containing 8
Gene Name (Vector)
coiled-coil domain containing 8
Gene Symbol
CCDC8
HGNC ID
HGNC:25367
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1617
ORF Size (bp)
1617 bp
Protein Name (eCommerce)
Coiled-coil domain-containing protein 8
RefSeq ID
NM_032040
RefSeq Synonyms
NM_032040, BC025243,
Research Areas
Kinase/Phosphatase
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
CCDC8 (coiled-coil domain containing 8) contains one coiled coil domain. The function of CCDC8 has not been reported.
UniGene ID
Hs.97876
UniProt ID (eCommerce)
Q9H0W5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.