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human CAPN3 shRNA silencing Adenovirus

Name 
Ad-h-CAPN3-shRNA
Cat No 
shADV-204047
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CAPN3.

shADV-204047
Ad-h-CAPN3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CAPN3 (calpain 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CANP3; CANPL3; LGMD2; LGMD2A; nCL-1; p94
Description (Vector)
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Gene ID
825
Gene Name (Vector)
calpain 3
Gene Symbol
CAPN3
HGNC ID
HGNC:1480
ORF Size (aa)
2466
ORF Size (bp)
2466 bp
RefSeq ID
NM_000070
RefSeq Synonyms
NM_173090, NM_173089, NM_173088, NM_173087, NM_024344, NM_000070, BC146672, BC146649, BC003521, BC003169,
Species
human
UniGene ID
Hs.143261

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.